SamPlexer - smarter sequencing, all around

Get ready to optimize the genome sequencing library preparation with the power of digital twins and advances bioinformatics algorithms

DNA Sequencing

has disrupted Life Science: with sequencing we better understand how do living systems work, we clarified the basis of numerous disease, and it helps us to design novel medicines in a matter of days.

Library preparation –
the final gatekeeper of truly democratized sequencing.

Cost per Sequenced Megabase
Cost (in $) per Mb

While the efficiency of sequencing devices has skyrocketed in the recent years, another integral step for sequencing – Library preparation has seen almost no innovation.​

In fact, it is currently the major financial and operational bottleneck for sequencing applications.​

Cost of Library preparaion in the last decade
Cost (in $) per Library prep

Library preparation still has high costs, long turn-around time and the current solutions to these problems are costly and laborious.


The issue of library preparation becomes even more apparent if we compare the relative cost of sequencing vs library preparation:
Human exome sequencing
Bacterial genome sequencing
Human exome sequencing
Bacterial genome sequencing
Sequencing
Library preparation

But there is a solution to this…

SamPlexer, the first SoftOmics suite, is a next generation computational platform​ that dramatically reduces the cost and time for library preparation,​ making sequencing cheaper, faster and more sustainable.

Smarter Science Starts with Smarter Sequencing​

Using the power of advanced bioinformatics algorithms, Samplexer first creates a digital twin of a sequencing experiment, and designs an optimized multiplexing strategy where samples with sufficiently different genetic material can be mixed and sequenced as one single sample.
After the sequencing of this combined sample is done, Samplexer performs in-silico sample demultiplexing, yielding the data of initial samples

SamPlexer saves

Up to 90% of LP cost

Up to 90% of time

Reduces lab waste and consumable

SamPlexer has major advantages

It requires no reagents, equipment or expertise, making it easy to use, affordable and scalable

It is compatible with any type of sequencing application and down-stream analysis

It can be used with other LP optimization methods allowing to further increase sequencing capacity

SamPlexer is used by our early adopters

SamPlexer will be the new disrupting tool for sequencing more samples in a cheaper and faster way, without compromising the quality of the results, while requiring minimal investments and efforts.

Who we are​

We develop software for optimization and management of pharma, biotech and life science projects. 

SoftOmics is a spin-off from Barcelona Supercomputing Centre, Institute for Research in Biomedicine and ICREA